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Peptic Ulcer Diseases and Conditions
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What is a peptic ulcer?

A peptic ulcer is a sore in the lining of your stomach or duodenum. The duodenum is the first part of your small intestine. If peptic ulcers are found in the stomach, they're called gastric ulcers. If they're found in the duodenum, they're called duodenal ulcers. You can have more than one ulcer.

Many people have peptic ulcers. Peptic ulcers can be treated successfully. Seeing your doctor is the first step.

What are the symptoms of peptic ulcers?

A burning pain in the gut is the most common symptom. The pain

feels like a dull ache
comes and goes for a few days or weeks
starts 2 to 3 hours after a meal
comes in the middle of the night when your stomach is empty
usually goes away after you eat

Other symptoms are

losing weight
not feeling like eating
having pain while eating
feeling sick to your stomach
vomiting


Some people with peptic ulcers have mild symptoms. If you have any of these symptoms, you may have a peptic ulcer and should see your doctor.

What causes peptic ulcers?

Peptic ulcers are caused by

bacteria called Helicobacter pylori, or H. pylori for short
nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen
other diseases

Your body makes strong acids that digest food. A lining protects the inside of your stomach and duodenum from these acids. If the lining breaks down, the acids can damage the walls. Both H. pylori and NSAIDs weaken the lining so acid can reach the stomach or duodenal wall.

H. pylori causes almost two-thirds of all ulcers. Many people have H. pylori infections. But not everyone who has an infection will develop a peptic ulcer.

Most other ulcers are caused by NSAIDs. Only rarely do other diseases cause ulcers.

To read the rest of this excellent article on peptic ulcers, produced by the National Digestive Diseases Information Clearinghouse, please click here: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm


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September 2008