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Lyme Disease
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In the early 1970s, a mysterious clustering of arthritis cases occurred among children in Lyme, Connecticut, and surrounding towns. Medical experts soon recognized the illness as a distinct disease, which they called Lyme disease. They subsequently described the signs and symptoms of Lyme disease, established the usefulness of antibiotics for treating it, identified the deer tick as the key to its spread, and isolated the bacterium that caused it.

Lyme disease is still mistaken for other ailments, and it continues to pose many other challenges, including the following
• It can be difficult to diagnose
• It can be troublesome to treat in its later phases
• A number of different ticks can transmit diseases with
symptoms similar to Lyme disease
• Deer ticks can transmit diseases other than Lyme disease

Symptoms

Erythema Migrans
Usually, the first symptom of Lyme disease is a red rash known as erythema migrans (EM). The telltale rash starts as a small red spot at the site of the tick bite. The spot expands over a period of days or weeks, forming a circular or oval-shaped rash. Sometimes the rash resembles a bull’s eye, appearing as a red ring surrounding a clear area with a red center. The rash, which can range in size from that of a dime to the width of your back, appears within a few weeks of a tick bite and usually at the site of the bite. As infection spreads, rashes can appear at different sites on the body.

Erythema migrans is often accompanied by symptoms such as fever, headache, stiff neck, body aches, and fatigue. Although these flu-like symptoms may resemble those of common viral infections, Lyme disease symptoms tend to persist or may come and go.

Arthritis
After several months of B. burgdorferi infection, slightly more than half of people not treated with antibiotics develop recurrent attacks of painful and swollen joints that last a few days to a few months. The arthritis can shift from one joint to another. The knee is most commonly affected. About 10 to 20 percent of untreated people will go on to develop chronic (long-lasting) arthritis.

Neurologic Symptoms
Lyme disease also can affect your nervous system, causing symptoms such as
• Stiff neck and severe headache (meningitis)
• Temporary paralysis of facial muscles (Bell’s palsy)
• Numbness, pain, or weakness in the limbs
• Poor muscle movement

More subtle changes such as memory loss, difficulty concentrating, and a change in mood or sleep habits also have been associated with Lyme disease. Nervous system problems usually develop several weeks, months, or even years following an untreated infection. These symptoms often last for weeks or months and may return.

Less commonly, untreated people may develop other problems weeks, months, or even years after infection. These include

Heart Problems
Fewer than 1 out of 10 people with Lyme disease develop heart problems, such as irregular heartbeat, which can start with dizziness or shortness of breath. These symptoms rarely last more than a few days or weeks. Such heart problems generally show up several weeks after infection.

Other Symptoms
Less commonly, Lyme disease can result in eye inflammation, hepatitis (liver disease), and severe fatigue, although none of these problems is likely to appear without other Lyme disease symptoms being present.

To read the rest of this article (including diagnosis and treatment information) from the National Institute of Allergy and Infectious Diseases, please click here: http://www.niaid.nih.gov/publications/Lyme_Disease_%20Final07-12-05.pdf


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November 2007